A Closer Look at Some Medical Use of Green Persian Walnut Shell

A Review: Green Persian Walnut Shell

Authors

DOI:

https://doi.org/10.1071/ejmbs.v3i1.28

Keywords:

Hyrcanian, Anti-cancer, medicinal effects, traditional medicine, Walnut

Abstract

Persian walnut (Juglans regia L) is a tree species that has been of interest to humans since its medicinal and nutritional effects. The wild population of this species has been recorded in the temperate and semi-arid mountainous regions of Central Asia, East and South Asia, the Middle East and the Caucasus region. The origin of Iran's walnut communities is in the Hyrcanian forest in the north of Iran. Walnut is a source of various medicinal compounds such as various biologically active substances such as polyphenols, flavonoids, steroids, phospholipids, triterpenes, kinins, fatty acids, tannins, gallic acid and ellagic acid, and plays an important role in medicine, especially in traditional Iranian medicine. All these compounds have turned walnut into an important commercial product that is of high value in the pharmaceutical and food industry. In this study, various medicinal effects of this valuable species such as anti-cancer, anti-oxidant and anti-diabetic effects have been investigated according to recent researches and it shows that depending on the different climatic conditions, the medicinal compounds of walnut can change and this phenomenon is necessary. It creates more research in this field.

References

Ahandani, E.A., Gawwad, M. R. A., Yavari, A. (2013). Extraction and preparation of psoralen from different plant part of Psoralea corylifolia and psoralen increasing with some elicitors. J Plant Biol, 2, 25-37.

Ahandani, E.A., Ramandi, H.D., Sarmad, J., Samani, M.A., Yavari, A., Ahandani, R.A. (2014). Evaluation of morphological diversity among somepersian walnut accessions (Juglans regia L.) in Guilan, Northern Iran. Int J Plant Biol Res, 2(3), 1015.

Akgül, H., Nur, A. D., Sevindik, M., Doğan, M. (2016). Tricholoma terreum ve Coprinus micaceus’ un bazı biyolojik aktivitelerinin belirlenmesi. Artvin Çoruh Üniversitesi Orman Fakültesi Dergisi, 17(2), 158-162.

Alinia-Ahandani, E. (2018a). Medicinal plants with disinfectant effects. J Pharm Sci Res, 10, 1-1.

Alinia-Ahandani, E., Alizadeh-Terepoei, Z., Boghozian, A. (2019). Positive role of green tea as an anti-cancer biomedical source in Iran northern. health-promotion, 6(13), 15-18.

Alinia-Ahandani, E., Alizadeh-Terepoei, Z., Sheydaei, M., Peysepar-Balalami, F. (2020). Assessment of soil on some heavy metals and its pollution in Roodsar-Iran. Biomed J Sci & Tech Res, 28(5), 21977-21979.

Alinia-Ahandani, E., Fazilati, M., Boghozian, A., Alinia-Ahandani, M. (2019). Effect of ultraviolet (UV) radiation bonds on growth and chlorophyll content of Dracocephalum moldavica L herb. J Biomol Res Ther, 8(1), 1-4.

Alinia-Ahandani, E., Nazem, H., Boghozian, A., Alizadeh, Z. (2019). Hepatitis and some effective herbs: A review. EAS J Parasitol Infect Dis, 1(1), 20-27.

Alinia-Ahandani, E., Sheydaei, M., Shirani-Bidabadi, B., Alizadeh-Terepoei, Z. (2020). Some effective medicinal plants on cardiovascular diseaaes in Iran-a review. J Glob Trends Pharm Sci, 11(3), 8021-8033.

Aryapak, S., Ziarati, P. (2014). Nutritive value of Persian walnut (Juglans regia L.) Orchards. Am. Eurasian J. Agric. Environ. Sci, 14, 1228-1235.

Bahmani, M., Shirzad, H., Majlesi, M., Shahinfard, N., Rafieian-Kopaei, M. (2014). A review study on analgesic applications of Iranian medicinal plants. Asian Pac J Trop Med, 7, S43-S53.

Bedia, B., Çelik, İ., Turan, A. (2019). Determination of Antioxidant Effect of Walnut (Juglans regia L.) on Lung and Muscle Tissue. Doğu Fen Bil Der, 2(1), 29-39.

Chauhan, A., Chauhan, V. (2020). Beneficial effects of walnuts on cognition and brain health. Nutrients, 12(2), 550.

Croitoru, A., Ficai, D., Craciun, L., Ficai, A., Andronescu, E. (2019). Evaluation and exploitation of bioactive compounds of walnut, Juglans regia. Curr Pharm Des, 25(2), 119-131.

Delaviz, H., Mohammadi, J., Ghalamfarsa, G., Mohammadi, B., Farhadi, N. (2017). A review study on phytochemistry and pharmacology applications of Juglans regia plant. Pharmacogn Rev, 11(22), 145.

Fukuda, T., Ito, H., Yoshida, T. (2004). Effect of the walnut polyphenol fraction on oxidative stress in type 2 diabetes mice. Biofactors, 21(1‐4), 251-253.

Habibi, A., Hamedpour-Darabi, M., Vahdati, K. (2022). Local cultural values of Persian walnut in Iran. The Cultural Value of Trees, 162-173.

Hassani, D., Sarikhani, S., Dastjerdi, R., Mahmoudi, R., Soleimani, A., Vahdati, K. (2020). Situation and recent trends on cultivation and breeding of Persian walnut in Iran. Scientia Horticulturae, 270, 109369.

Jafri Sayadi, M. H., Vahdati, K., Mozafari, J., Mohajer, M. R. M., Leslie, C. A. (2011). Natural Hyrcanian populations of Persian walnut (Juglans regia L.) in Iran. In I International Symposium on Wild Relatives of Subtropical and Temperate Fruit and Nut Crops, 948, 97-101.

Jahanbani, R., Ghaffari, S. M., Salami, M., Vahdati, K., Sepehri, H., Sarvestani, N. N., Moosavi-Movahedi, A. A. (2016). Antioxidant and anticancer activities of walnut (Juglans regia L.) protein hydrolysates using different proteases. Plant Foods Hum Nutr, 71(4), 402-409.

Jaimand, K., Baghai, P., Rezaee, M. B., Sajadipoor, S. A., Nasrabadi, M. (2004). Extraction and Identification of Juglone from Leaves and fresh peels of Juglans regia L. by High-Performance liquid Chromatography. J Appl Res Med Aromat Plants, 20(3), 323-331.

Kına, E., Uysal, İ., Mohammed, F. S., Doğan, M., Sevindik, M. (2021). In-vitro antioxidant and oxidant properties of Centaurea rigida. Turkish JAF Sci Tech, 9(10), 1905-1907.

Liu, M., Li, C., Cao, C., Wang, L., Li, X., Che, J., Liu, X. (2021). Walnut fruit processing equipment: academic insights and perspectives. Food Engineering Reviews, 13(4), 822-857.

Pehlivan, M., Mohammed, F. S., Şabik, A. E., Kına, E., Dogan, M., Yumrutaş, Ö., Sevindik, M. (2021). Some Biological activities of ethanol extract of Marrubium globosum. Turkish JAF Sci Tech, 9(6), 1129-1132.

Rusu, M. E., Georgiu, C., Pop, A., Mocan, A., Kiss, B., Vostinaru, O., Popa, D. S. (2020). Antioxidant effects of walnut (Juglans regia L.) kernel and walnut septum extract in a D-galactose-induced aging model and in naturally aged rats. Antioxidants, 9(5), 424.

Sevindik, M., Akgül, H., Günal, S., Doğan, M. (2016). Pleurotus ostreatus’ un doğal ve kültür formlarının antimikrobiyal aktiviteleri ve mineral madde içeriklerinin belirlenmesi. J Kast Forf, 16(1), 153-156.

Sevindik, M., Akgul, H., Pehlivan, M., Selamoglu, Z. (2017). Determination of therapeutic potential of Mentha longifolia ssp. longifolia. Fresen Environ Bull, 26(7), 4757-4763.

Sevindik, M., Akgul, H., Korkmaz, A. I., Sen, I. (2018). Antioxidant potantials of Helvella leucomelaena and Sarcosphaera coronaria. J Bacteriol Mycol, 6(2), 00173.

Sheydaei, M., Alinia-Ahandani, E. (2020). Cancer and Polymeric-Carriers. Biomed J Sci Tech Res 31(2), 24107- 24110.

Sheydaei, M., Alinia-Ahandani, E. (2021). Breast cancer and the role of polymer-carriers in treatment. Biomed J Sci Technol Res, 34(5), 27057-27061.

Sheydaei, M. Edraki, M., Javanbakht, Sh., Alinia-Ahandani, E., Soleimani, M, Zerafatkhah, A. (2021) Poly(butylene disulfide) and poly(butylene tetrasulfide): Synthesis, cure and investigation of polymerization yield and effect of sulfur content on mechanical and thermophysical properties. Phosphorus Sulfur Silicon Relat Elem, 196(6), 578-584.

Shigaeva, J., Darr, D. (2020). On the socio-economic importance of natural and planted walnut (Juglans regia L.) forests in the Silk Road countries: A systematic review. For Policy Econ, 118, 102233.

Taheri, A., Mirghazanfari, S. M., Dadpay, M. (2020). Wound healing effects of Persian walnut (Juglans regia L.) green husk on the incision wound model in rats. Eur J Transl Myol, 30(1), 210-218.

Uysal, İ., Mohammed, F. S., Şabik, A. E., Kına, E., Sevindik, M. (2021). Antioxidant and Oxidant status of medicinal plant Echium italicum collected from different regions. Turkish JAF Sci Tech, 9(10), 1902-1904.

Verma, G., Sharma, V. (2020). A Scientific Update on Juglans Regia Linn. Asian J Pharm Res Dev, 8(3), 166-175.

Vieira, V., Pereira, C., Abreu, R. M., Calhelha, R. C., Alves, M. J., Coutinho, J. A., Ferreiraa, O., Barros, L., Ferreira, I. C. (2020). Hydroethanolic extract of Juglans regia L. green husks: A source of bioactive phytochemicals. Food Chem Toxicol, 137, 111189.

Vinson, J. A., Cai, Y. (2012). Nuts, especially walnuts, have both antioxidant quantity and efficacy and exhibit significant potential health benefits. Food Funct, 3(2), 134-140.

Wang, J., Wu, T., Fang, L., Liu, C., Liu, X., Li, H., Min, W. (2020). Anti-diabetic effect by walnut (Juglans mandshurica Maxim.)-derived peptide LPLLR through inhibiting α-glucosidase and α-amylase, and alleviating insulin resistance of hepatic HepG2 cells. J Funct Foods, 69, 103944.

Wang, X., Zhao, M., Su, G., Cai, M., Zhou, C., Huang, J., Lin, L. (2015). The antioxidant activities and the xanthine oxidase inhibition effects of walnut (Juglans regia L.) fruit, stem and leaf. Int J Food Sci, 50(1), 233-239.

Wei, B., Zhu, H., Wang, K., Liu, S., Dai, Y., Liu, D., Sun, H. (2022). Antitumor and immunomodulation of total flavonoids from the green peep of Juglans regia L. in mouse forestomach carcinoma gastric cancer-bearing mice. Phcog Mag, 18(78), 328.

Zhao, H., Li, J., Zhao, J., Chen, Y., Ren, C., Chen, Y. (2018). Antioxidant effects of compound walnut oil capsule in mice aging model induced by D-galactose. Food Nutr Res, 62, doi: 10.29219/fnr.v62.1371

Zhao, M. H., Jiang, Z. T., Liu, T., Li, R. (2014). Flavonoids in Juglans regia L. leaves and evaluation of in vitro antioxidant activity via intracellular and chemical methods. Sci World J, doi:10.1155/2014/303878

Downloads

Published

2023-06-30

How to Cite

Hajipour, S. ., Alinia-Ahandani, E. ., & Selamoğlu, Z. (2023). A Closer Look at Some Medical Use of Green Persian Walnut Shell: A Review: Green Persian Walnut Shell. Eurasian Journal of Medical and Biological Sciences, 3(1), 1–7. https://doi.org/10.1071/ejmbs.v3i1.28

Issue

Section

Review Articles

Most read articles by the same author(s)

1 2 > >>