Anticancer Mechanisms of Action of Macrofungus Extracts

Emre Cem Eraslan, Bürke Çırçırlı, Aysun Özkan, Hasan Akgül


Mushrooms are  delicious and nutritious food group and have been consumed by many societies in different parts of the world throughout history. Natural products derived from mushrooms have also been excellent source of medicine. They produce structurally various metabolites, many of which have served as excellent pharmaceutical sources. The most common types of cancer in the world are lung cancer, breast cancer, colon cancer, prostate cancer, skin cancer, thyroid cancer, stomach cancer, liver cancer, ovarian cancer, brain tumors and cervical cancer. Cancer cases are the forefront of death causes in the world along with cardiovascular diseases. It is a health problem that brings socioeconomically responsibilty in the countries where it is seen. Cancer is a growing health problem worldwide. Epidemiological studies in societies confirm that fungi are the primary sources of drugs used in reducing cancer prevalence and preventing cancer-related deaths. As a result, they are potential candidates for natural anticancer drugs, thanks to more comprehensive future research on the anti-cancer activities of macrofungus extracts. In this study, information about the anticancer potential of macrofungi has been given.


Anticancer; Macrofungi; Medicinal mushroom; Natural drugs

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